BOTOX
Before & After Photos

Moderate to Severe Lateral Canthal Lines and Glabellar Lines

BEFORE       AFTER

BEFORE

AFTER

BEFORE

AFTER

Moderate to Severe Forehead Lines, Lateral Canthal Lines, and Glabellar Lines

BEFORE       AFTER

BEFORE

AFTER

Actual patients. Results may vary.
Photos taken at maximum smile and at maximum frown before treatment with BOTOX® Cosmetic (onabotulinumtoxinA), and taken at maximum smile after treatment with BOTOX® Cosmetic at day 7, and taken at maximum frown after treatment with BOTOX® Cosmetic at day 7 and months 3 and 4.
Moderate to Severe Lateral Canthal Lines
In clinical trials at day 30, 26.1% (58/222) and 20.3% (62/306) of patients demonstrated a ≥ 2-grade improvement from baseline in crow’s feet line severity at maximum smile as compared to 1.3% (3/223) and 0% (0/306) for placebo, as assessed by both investigators and subjects.1
Moderate to Severe Glabellar Lines
In clinical trials at day 7, 74% (299/405) of patients demonstrated none or mild glabellar line severity at maximum frown as compared to 6% (8/132) in placebo, as assessed by investigators; at day 30, 80% (325/405) of patients demonstrated the same as compared to 3% (4/132) in placebo; at month 3, 48% (192/403) of patients demonstrated the same as compared to 2% (3/128) in placebo; at month 4, 25% (102/403) of patients demonstrated the same as compared to 2% (2/128) in placebo.1
In clinical trials at day 7, 82% (334/405) of patients achieved at least a moderate improvement in their glabellar line appearance compared to 9% (12/132) in placebo, as evaluated by patients; at day 30, 89% (362/405) of patients assessed the same as compared to 7% (9/132) in placebo; at month 3, 63% (254/403) of patients assessed the same as compared to 3% (4/128) in placebo; at month 4, 39% (157/403) of patients assessed the same as compared to 1% (1/128) in placebo.1
1. BOTOX® Cosmetic Prescribing Information, October 2017.